Colace Regular Strength Stool Softener 100 mg Capsules, 30 Ct. Colace Capsules are the #1 stool softener brand recommended by doctors. For gentle reliable relief from occasional constipation (irregularity). Stimulant free for comfortable relief. Generally produces bowel movement in 12 to 72 hours. Colace has been trusted by doctors and patients for nearly 6O years to relieve occasional constipation. Colace Capsules active ingredient is Docusate Sodium, which allows water and fats to get into the stool, helping to soften and make passing it more comfortable.