Picaridin is the One of the longest lasting repellents available, it provides up to 14 hours of protection against mosquitoes and ticks (using the lotion; up to 12 hours for spray models), and up to 8 hours against a variety of flies, chiggers, and gnats. perfect balance of efficacy, safety, and user-friendliness. It repels a wide variety of pests including mosquitoes, ticks, biting flies, sand flies, gnats, chiggers, and midges.